About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cyclocytidine is a cytidine analogue that is metabolized into cytarabine (AraC) in vivo. It inhibits DNA polymerase, incorporates into DNA and halts chain elongation, leading to apoptosis in rapidly dividing cells. Its cyclic structure provides improved stability and pharmacokinetic characteristics.
Benefits and Advantages
Used in nucleosideanalogue research, leukemiamodel studies, DNApolymerase inhibition assays, and prodrugactivation pathway modelling.
Side Effects and Risks
Risks include bonemarrow suppression, hepatotoxicity, mucositis, neurotoxicity and immunosuppression. Handle with cytotoxicdrug containment.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C9H14N3O5 |
|---|---|
| Molecular Weight | 225.20 g/mol |
| CAS Number | 31698-14-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | H2O 200 ( mg/mL) |
| Purity | Purity information is available upon request (COA). |
| Synonym | ANCITABINE; Cyclocytidine; 31698-14-3; 2,2'-Cyclocytidine; Ancitabina |
| IUPAC/Chemical Name | (2R,4R,5R,6S)-4-(hydroxymethyl)-10-imino-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-5-ol |
| InChl Key | BBDAGFIXKZCXAH-CCXZUQQUSA-N |
| InChl Code | InChI=1S/C9H11N3O4/c10-5-1-2-12-8-7(16-9(12)11-5)6(14)4(3-13)15-8/h1-2,4,6-8,10,13-14H,3H2/t4-,6-,7+,8-/m1/s1 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
