About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Colestyramine (cholestyramine) is a cationic anionexchange resin that binds bile acids with high affinity, interrupting enterohepatic circulation. This depletion of bile acids stimulates hepatic conversion of cholesterol into new bile acids, reduces LDL cholesterol and alters lipid and glucose homeostasis.
Benefits and Advantages
Used in enterohepaticcirculation research, lipidmetabolism models, bileacid signalling studies, toxinbinding assays and gastrointestinalsequestration analysis.
Side Effects and Risks
Risks include constipation, bloating, interference with fatsoluble vitamin absorption, hypertriglyceridemia and drugbinding interactions. Handle with GIactive polymeric material precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C27H44ClN |
|---|---|
| Molecular Weight | 418.1 g/mol |
| CAS Number | 11041-12-6 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Colestyramine; Cholestyramine (Technical Grade); Colestyramine CRS |
| IUPAC/Chemical Name | 2-methylbutane;trimethyl-[[4-(5-phenylhexan-3-yl)phenyl]methyl]azanium;chloride |
| InChl Key | KZCULXLKDWCGKV-UHFFFAOYSA-M |
| InChl Code | InChI=1S/C22H32N.C5H12.ClH/c1-6-20(16-18(2)21-10-8-7-9-11-21)22-14-12-19(13-15-22)17-23(3,4)5;1-4-5(2)3;/h7-15,18,20H,6,16-17H2,1-5H3;5H,4H2,1-3H3;1H/q+1;;/p-1 |
| References |
3D Conformer.
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