DIHYDROTESTOSTERONE – DHT
Dihydrotestosterone (DHT) is a potent androgen derived from testosterone via 5‑α‑reductase. It binds androgen receptors with high affinity, driving male sexual development and hair follicle regulation. Benefits include essential roles in puberty and reproductive function. Side effects of excess include hair loss, acne, and prostate enlargement.
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Product Description
Mechanism of Action
Dihydrotestosterone is a potent endogenous androgen formed by 5‑α‑reduction of testosterone. It binds the androgen receptor (AR) with several‑fold higher affinity than testosterone and initiates transcription of AR‑regulated genes. DHT plays key roles in sexual differentiation, hair‑follicle physiology and prostate biology.
Benefits and Advantages
Used in androgen‑receptor signalling studies, endocrine‑axis modelling, prostate‑cell research, hair‑follicle pathway analysis and steroid‑receptor binding assays.
Side Effects and Risks
Risks include androgenic effects, acne, prostate enlargement, mood alterations, lipid changes and endocrine disruption. Handle with potent androgen‑hormone precautions.
Datasheet
| Molecular Formula | C19H30O2 |
|---|---|
| Molecular Weight | 290.44 g/mol |
| CAS Number | 521-18-6 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | 17-Hydroxyandrostan-3-one; 17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one; 17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta(a)phenanthren-3-one; RefChem:1057624; Anaprotin |
| IUPAC/Chemical Name | (5α)-androstan-17β-ol-3-one |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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