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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Corticosterone hemisuccinate is a watersoluble ester of corticosterone used for improved delivery and controlled hydrolysis. After enzymatic cleavage, free corticosterone activates GRmediated transcription, suppresses inflammatory cascades and modulates metabolic homeostasis.
Benefits and Advantages
Used in soluble glucocorticoiddelivery studies, stresshormone modulation research, inflammation models, and receptoractivation kinetics experiments.
Side Effects and Risks
Risks include typical glucocorticoid effects: immunosuppression, adrenal inhibition, glucose elevation and behavioural changes. Handle as a steroid prodrug.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C25H34O7 |
|---|---|
| Molecular Weight | 446.5 g/mol |
| CAS Number | 10215-77-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Corticosterone-21-hemisuccinate; 10215-77-7; Corticosterone hemisuccinate; IU50V885SP; Pregn-4-ene-3,20-dione, 21-(3-carboxy-1-oxopropoxy)-11-hydroxy-, (11beta)- |
| IUPAC/Chemical Name | 4-[2-[(8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid |
| InChl Key | KEECMXYFGNWLEA-BIGDRKAKSA-N |
| InChl Code | InChI=1S/C25H34O7/c1-24-10-9-15(26)11-14(24)3-4-16-17-5-6-18(25(17,2)12-19(27)23(16)24)20(28)13-32-22(31)8-7-21(29)30/h11,16-19,23,27H,3-10,12-13H2,1-2H3,(H,29,30)/t16-,17-,18+,19-,23+,24-,25-/m0/s1 |
| References |
3D Conformer.
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