CORTICOSTERONE BASE

Corticosterone (micronized) provides improved absorption for with similar glucocorticoid activity. Side effects include hormonal imbalance and immune suppression. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 70ed871d0c15 Category: Tag:

Product Description


Mechanism of Action

Corticosterone base is the primary glucocorticoid in many nonhuman vertebrates. It diffuses into cells and binds cytosolic glucocorticoid receptors, initiating transcriptional suppression of inflammatory genes and upregulation of metabolic, antistress and gluconeogenic pathways.

Benefits and Advantages

Used in HPAaxis research, stressresponse modelling, glucocorticoidreceptor signalling studies, immunomodulation assays and behaviouralendocrinology experiments.

Side Effects and Risks

Risks include metabolic dysregulation, immune suppression, behavioural alterations and endocrineaxis disruption. Handle with steroidhormone safety procedures.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C21H28O5

Molecular Weight

346.45 g/mol

CAS Number

50-22-6

Storage Condition

Store in a cool, dry place; protect from light

Solubility

Soluble in water

Purity

Purity information is available upon request (COA).

Synonym

chlorpropham; 101-21-3; CHLOROPROPHAM; Chloro-IPC; CIPC

IUPAC/Chemical Name

(11β)-11,21-dihydroxy-pregn-4-ene-3,20-dione

InChl Key

Unavailable

InChl Code

Unavailable

References

PubChem; ChemBL; FDA;

3D Conformer.

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