CORTICOSTERONE BASE
Corticosterone (micronized) provides improved absorption for with similar glucocorticoid activity. Side effects include hormonal imbalance and immune suppression. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Corticosterone base is the primary glucocorticoid in many nonhuman vertebrates. It diffuses into cells and binds cytosolic glucocorticoid receptors, initiating transcriptional suppression of inflammatory genes and upregulation of metabolic, antistress and gluconeogenic pathways.
Benefits and Advantages
Used in HPAaxis research, stressresponse modelling, glucocorticoidreceptor signalling studies, immunomodulation assays and behaviouralendocrinology experiments.
Side Effects and Risks
Risks include metabolic dysregulation, immune suppression, behavioural alterations and endocrineaxis disruption. Handle with steroidhormone safety procedures.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C21H28O5 |
|---|---|
| Molecular Weight | 346.45 g/mol |
| CAS Number | 50-22-6 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | chlorpropham; 101-21-3; CHLOROPROPHAM; Chloro-IPC; CIPC |
| IUPAC/Chemical Name | (11β)-11,21-dihydroxy-pregn-4-ene-3,20-dione |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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