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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Fusidate sodium is the sodium salt of fusidic acid, a steroidlike antibiotic that inhibits bacterial protein synthesis by blocking elongation factor G (EFG)mediated translocation on the 70S ribosome. It is particularly active against staphylococci.
Benefits and Advantages
Used in EFG mechanism research, ribosomal translocation assays, staphylococcal resistance modelling and topical/systemic fusidicformulation studies.
Side Effects and Risks
Risks include hepatotoxicity, jaundice (systemic use), GI upset and local irritation with topical application. Handle with steroidalantibiotic precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C31H47NaO6 |
|---|---|
| Molecular Weight | 538.7 g/mol |
| CAS Number | 751-94-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Fusidate sodium; Sodium fusidate; 751-94-0; FUSIDIC ACID SODIUM SALT; Fucidine |
| IUPAC/Chemical Name | sodium (2Z)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetyloxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoate |
| InChl Key | HJHVQCXHVMGZNC-JCJNLNMISA-M |
| InChl Code | InChI=1S/C31H48O6.Na/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32;/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36);/q;+1/p-1/b26-20-;/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-;/m0./s1 |
| References |
3D Conformer.
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