FLUCLOXACILLIN

Flucloxacillin is a lactam antibiotic effective against penicillinaseproducing staphylococci. Side effects include rash, liver dysfunction, and GI upset. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 932e41fd7ebf Category: Tag:

Product Description


Mechanism of Action

Flucloxacillin is a lactamaseresistant isoxazolyl penicillin that binds PBPs and inhibits peptidoglycan crosslinking. It is specifically active against penicillinaseproducing Staphylococcus species.

Benefits and Advantages

Used in PBPbinding assays, lactamaseresistance studies and Grampositive antimicrobial research.

Side Effects and Risks

Risks include cholestatic hepatitis, rash and GI upset.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C19H17ClFN3O5S

Molecular Weight

453.9 g/mol

CAS Number

5250-39-5

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

5.45e-02 g/L

Purity

Purity information is available upon request (COA).

Synonym

Flucloxacillin; FLOXACILLIN; 5250-39-5; flucloxacilina; Flucloxacilline

IUPAC/Chemical Name

(2S,5R,6R)-6-[[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

InChl Key

UIOFUWFRIANQPC-JKIFEVAISA-N

InChl Code

InChI=1S/C19H17ClFN3O5S/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28)/t13-,14+,17-/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/21319;

3D Conformer.

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