ERYTHROMYCIN PROPIONATE
Erythromycin propionate is a topical macrolide antibiotic that inhibits bacterial protein synthesis, helping reduce acne-related inflammation. Benefits include reduced lesions and improved skin clarity. Side effects may include dryness, redness, and mild irritation. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Erythromycin propionate is a lipophilic ester that enhances tissue penetration and is hydrolyzed to active erythromycin. It inhibits bacterial protein synthesis by blocking 50S ribosomal translocation.
Benefits and Advantages
Used in esterprodrug research, enhancedpenetration macrolide modelling, topicaldelivery studies, and antibacterialmechanism assays.
Side Effects and Risks
Risks include skin irritation (topical forms), hepatotoxicity, and GI disturbances. Handle with propionateester precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C40H71NO14 |
|---|---|
| Molecular Weight | 790.0 g/mol |
| CAS Number | 134-36-1 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Erythromycin propionate; 134-36-1; Propionylerythromycin; Erythromycin, 2'-propionate; Monopropionylerythromycin |
| IUPAC/Chemical Name | [(2S,3R,4S,6R)-4-(dimethylamino)-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-oxacyclotetradec-6-yl]oxy]-6-methyloxan-3-yl] propanoate |
| InChl Key | TYQXKHPOXXXCTP-CSLYCKPJSA-N |
| InChl Code | InChI=1S/C40H71NO14/c1-15-27-40(11,48)33(44)22(5)30(43)20(3)18-38(9,47)35(55-37-32(53-28(42)16-2)26(41(12)13)17-21(4)50-37)23(6)31(24(7)36(46)52-27)54-29-19-39(10,49-14)34(45)25(8)51-29/h20-27,29,31-35,37,44-45,47-48H,15-19H2,1-14H3/t20-,21-,22+,23+,24-,25+,26+,27-,29+,31+,32-,33-,34+,35-,37+,38-,39-,40-/m1/s1 |
| References |
3D Conformer.
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