ERYTHROMYCIN STEARATE
Erythromycin stearate is an oral macrolide antibiotic used for respiratory and skin infections. It inhibits bacterial protein synthesis. Side effects include nausea, abdominal discomfort, and rare hepatotoxicity. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Erythromycin stearate is a hydrophobic salt designed to improve oral tolerability and acid resistance. After dissolution and absorption, it releases active erythromycin which blocks 50Smediated protein elongation.
Benefits and Advantages
Used in macrolideformulation improvement research, gastricacid stability studies, and oralbioavailability model systems.
Side Effects and Risks
Risks include mild hepatotoxicity, abdominal discomfort and hypersensitivity. Handle with macrolidesalt precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C55H103NO15 |
|---|---|
| Molecular Weight | 1018.4 g/mol |
| CAS Number | 643-22-1 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | less than 1 mg/mL at 72 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | ERYTHROMYCIN STEARATE; Abboticine; Bristamycin; 643-22-1; Gallimycin |
| IUPAC/Chemical Name | (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione;octadecanoic acid |
| InChl Key | YAVZHCFFUATPRK-YZPBMOCRSA-N |
| InChl Code | InChI=1S/C37H67NO13.C18H36O2/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;2-17H2,1H3,(H,19,20)/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;/m1./s1 |
| References |
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