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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cefuroxime is a second‑generation cephalosporin active against respiratory, ENT and soft‑tissue pathogens. It inhibits PBPs, blocking peptidoglycan crosslinking. It shows improved β‑lactamase stability and good penetration into respiratory tissues.
Benefits and Advantages
Used in respiratory‑pathogen research, β‑lactam SAR studies, pharmacokinetic comparisons, gram‑positive/negative susceptibility modelling and surgical‑prophylaxis pathway analysis.
Side Effects and Risks
Risks include allergic reactions, diarrhoea, dysbiosis, rare hepatic disturbances and possible nephrotoxicity. Handle with β‑lactam antibiotic precautions.
Datasheet
| Molecular Formula | C16H16N4O8S |
|---|---|
| Molecular Weight | 424.4 g/mol |
| CAS Number | 55268-75-2 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Freely soluble as sodium salt (145 mg/L) |
| Purity | Purity information is available upon request (COA). |
| Synonym | cefuroxime; 55268-75-2; Cephuroxime; Cefuroximo; Cefuroximum |
| IUPAC/Chemical Name | (6R,7R)-3-(carbamoyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| InChl Key | JFPVXVDWJQMJEE-IZRZKJBUSA-N |
| InChl Code | InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1 |
| References |
3D Conformer.
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