About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cephalexin monohydrate is a firstgeneration oral cephalosporin that inhibits bacterial cellwall synthesis through highaffinity binding to PBPs, blocking transpeptidation of peptidoglycan chains. The monohydrate form ensures stability and predictable oral absorption. Strong activity is seen against grampositive cocci and certain gramnegative bacilli.
Benefits and Advantages
Used in grampositive susceptibility profiling, lactam SAR research, staphylococcal cellwall studies, oral PK modelling, biofilmgrowth inhibition assays and earlygeneration cephalosporin mechanistic comparisons.
Side Effects and Risks
Risks include hypersensitivity, GI irritation, candidal overgrowth, rare renal inflammation and potential crossreactivity in penicillinallergic subjects. Handle under lactam containment standards.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C16H17N3O4S·H2O |
|---|---|
| Molecular Weight | 365.4 g/mol |
| CAS Number | 23325-78-2 |
| Storage Condition | Cephalexin capsules, tablets, and powder for oral suspension should be stored in tight containers at a temperature less than 40 °C, preferably between 15-30 °C. After reconstitution, cephalexin oral suspensions should be stored at 2-8 °C and discarded if not used within 2 wk. |
| Solubility | 10mg/mL |
| Purity | Purity information is available upon request (COA). |
| Synonym | Cephalexin monohydrate; 23325-78-2; cefalexin hydrate; 7-(D-alpha-Amino-alpha-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid monohydrate; CHEBI:3535 |
| IUPAC/Chemical Name | (6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate |
| InChl Key | AVGYWQBCYZHHPN-CYJZLJNKSA-N |
| InChl Code | InChI=1S/C16H17N3O4S.H2O/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9;/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23);1H2/t10-,11-,15-;/m1./s1 |
| References |
3D Conformer.
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