CEFROXADINE

Cefroxadine is an oral cephalosporin with grampositive and gramnegative coverage. Side effects include nausea, diarrhea, and rash. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 5e83f5487f2e Category: Tag:

Product Description


Mechanism of Action

Cefroxadine is a firstgeneration oral cephalosporin that interferes with bacterial cellwall synthesis by binding PBPs and inhibiting peptidoglycan crosslinking. It displays enhanced stability in acidic environments and good oral absorption, making it useful for upperrespiratory and softtissue pathogen research.

Benefits and Advantages

Applied in oral cephalosporin pharmacokinetic analysis, grampositive susceptibility modelling, lactam SAR studies, and staphylococcal/streptococcal resistance research. Serves as a reference compound for earlygeneration cephalosporins.

Side Effects and Risks

Risks include hypersensitivity, nausea, diarrhoea and rare haematologic disturbances. Use standard antimicrobial PPE.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C16H18N4O5S2

Molecular Weight

365.4 g/mol

CAS Number

51762-05-1

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

cefroxadine; Oraspor; 51762-05-1; Cefroxadin; Cgp 9000

IUPAC/Chemical Name

(6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

InChl Key

RDMOROXKXONCAL-UEKVPHQBSA-N

InChl Code

InChI=1S/C16H19N3O5S/c1-24-9-7-25-15-11(14(21)19(15)12(9)16(22)23)18-13(20)10(17)8-5-3-2-4-6-8/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/5284529;

3D Conformer.

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