About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cefradine is a firstgeneration cephalosporin structurally related to cephalexin. It binds PBPs, blocking crosslinking of peptidoglycan layers and compromising bacterial cellwall integrity. It shows strong grampositive activity with limited gramnegative effect. Its stability and oral bioavailability make it a reference compound for early cephalosporin development.
Benefits and Advantages
Used in historical lactam SAR research, grampositive susceptibility studies, cellwall biosynthesis modelling, pharmacokinetic absorption comparisons and resistancepathway investigations. Also applied in staphylococcal infection studies.
Side Effects and Risks
Risks include allergic reactions, GI irritation, rare nephrotoxicity and alteration of normal flora. Handle with lactam safety protocols.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C16H19N3O4S |
|---|---|
| Molecular Weight | 349.4 g/mol |
| CAS Number | 38821-53-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | cephradine; Cefradine; 38821-53-3; Cephradin; Anspor |
| IUPAC/Chemical Name | (6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| InChl Key | RDLPVSKMFDYCOR-UEKVPHQBSA-N |
| InChl Code | InChI=1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1 |
| References |
3D Conformer.
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