About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cefprozil is a secondgeneration oral cephalosporin that inhibits bacterial cellwall synthesis through highaffinity binding to penicillinbinding proteins (PBPs). This blocks transpeptidation reactions necessary for peptidoglycan crosslinking. Its structural side chain provides improved lactamase stability relative to firstgeneration agents, enhancing its effect against respiratory and softtissue pathogens. Cefprozil displays balanced grampositive and gramnegative coverage.
Benefits and Advantages
Used in respiratorypathogen modelling, lactam SAR research, oralabsorption pharmacokinetics, PBPaffinity testing and evaluation of communityacquired infection resistance trends. Also applied in biofilmformation studies and comparative cephalosporinpotency profiling.
Side Effects and Risks
Risks include hypersensitivity reactions, GI upset, dysbiosis, rare hepatic enzyme changes, and moderate risk of C. difficile overgrowth. Handle following standard antimicrobial precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C18H19N3O5S |
|---|---|
| Molecular Weight | 389.4 g/mol |
| CAS Number | 92665-29-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Cefzil; 92665-29-7; DTXSID6022767; BMY 28100; BMY-28100 |
| IUPAC/Chemical Name | (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-prop-1-enyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| InChl Key | WDLWHQDACQUCJR-PBFPGSCMSA-N |
| InChl Code | InChI=1S/C18H19N3O5S/c1-2-3-10-8-27-17-13(16(24)21(17)14(10)18(25)26)20-15(23)12(19)9-4-6-11(22)7-5-9/h2-7,12-13,17,22H,8,19H2,1H3,(H,20,23)(H,25,26)/t12-,13-,17-/m1/s1 |
| References |
3D Conformer.
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