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Product Description
Mechanism of Action
Fursultiamine (thiamine tetrahydrofurfuryl disulfide) is a lipophilic thiamine derivative that readily crosses biological membranes. After absorption, it is converted to thiamine and then to thiamine diphosphate, an essential cofactor for key oxidative‑decarboxylation and transketolase reactions in carbohydrate metabolism.
Benefits and Advantages
Used in vitamin B1 transport studies, energy‑metabolism research, neuroprotective thiamine‑pathway assays and pharmacokinetic comparison with water‑soluble thiamine salts.
Side Effects and Risks
Generally well tolerated; high doses may cause headache, nausea, allergic reactions or flushing. Handle with standard precautions for bioactive vitamin derivatives.
Datasheet
| Molecular Formula | C17H26N4O3S2 |
|---|---|
| Molecular Weight | 398.5 g/mol |
| CAS Number | 804-30-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | FURSULTIAMINE; 804-30-8; Fursultiamin; TTFD; Thiamine tetrahydrofurfuryl disulfide |
| IUPAC/Chemical Name | N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[(E)-5-hydroxy-3-(oxolan-2-ylmethyldisulfanyl)pent-2-en-2-yl]formamide |
| InChl Key | JTLXCMOFVBXEKD-FOWTUZBSSA-N |
| InChl Code | InChI=1S/C17H26N4O3S2/c1-12(16(5-6-22)26-25-10-15-4-3-7-24-15)21(11-23)9-14-8-19-13(2)20-17(14)18/h8,11,15,22H,3-7,9-10H2,1-2H3,(H2,18,19,20)/b16-12+ |
| References |
3D Conformer.
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