GABADAXOL

Gabadaxol is a GABAA receptor agonist investigated for sleep disorders. Side effects include sedation, dizziness, and cognitive impairment. Only GMP materials will be supplied, logistics all according to GDP.

SKU: cd875d0bc96a Category: Tag:

Product Description


Mechanism of Action

Gabadaxol (gaboxadol derivative) is a selective extrasynaptic GABAA receptor agonist that preferentially activates subunitcontaining GABAA receptors, enhancing tonic inhibition rather than phasic synaptic currents. This produces distinct sedative and sleepmodulating effects.

Benefits and Advantages

Used in sleeparchitecture research, tonic vs. phasic GABAergic signalling studies, receptorsubtype pharmacology and CNS drugdiscovery models.

Side Effects and Risks

Risks include sedation, dizziness, ataxia, cognitive impairment and, at high doses, respiratory depression. Handle with CNSdepressant and GABAagonist precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C7H10N2O2

Molecular Weight

144.17 g/mol

CAS Number

67469-80-5

Storage Condition

Store in a cool, dry place; protect from light

Solubility

Soluble in water

Purity

Purity information is available upon request (COA).

IUPAC/Chemical Name

4-aminobutanamide

InChl Key

Unavailable

InChl Code

Unavailable

References

PubChem; ChemBL; FDA;

3D Conformer.

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