FURACILIN
Furacilin (nitrofurazone) is an antimicrobial inhibiting bacterial enzymes. Side effects include skin irritation and allergic reactions.
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Product Description
Mechanism of Action
Furacilin (nitrofurazone‑type nitrofuran) is a nitrofuran antimicrobial that undergoes enzymatic reduction of its nitro group within bacterial cells, generating reactive intermediates that attack DNA, proteins and other macromolecules. This multi‑target damage leads to inhibition of replication and cell death.
Benefits and Advantages
Used in topical antimicrobial research, nitrofuran redox‑cycling studies, DNA‑damage assays and wound‑care formulation development.
Side Effects and Risks
Risks include contact dermatitis, local irritation, rare systemic hypersensitivity and potential mutagenicity with chronic exposure. Handle with nitrofuran‑class safety measures.
Datasheet
| Molecular Formula | C6H6N4O7 |
|---|---|
| Molecular Weight | 198.14 g/mol |
| CAS Number | 59-87-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | less than 1 mg/mL at 66 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | nitrofurazone; 59-87-0; Nitrofural; Furacilin; Furacin |
| IUPAC/Chemical Name | [(E)-(5-nitrofuran-2-yl)methylideneamino]urea |
| InChl Key | IAIWVQXQOWNYOU-FPYGCLRLSA-N |
| InChl Code | InChI=1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+ |
| References |
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