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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Product Description
Mechanism of Action
Dutogliptin is a selective DPP‑4 inhibitor that prevents degradation of incretin hormones (GLP‑1, GIP). This prolongs insulinotropic signalling, enhances glucose‑dependent insulin release and suppresses inappropriate glucagon secretion.
Benefits and Advantages
Used in incretin‑pathway modulation studies, DPP‑4 inhibition assays, glucose‑regulation modelling, and combination‑therapy research with GLP‑1 agonists.
Side Effects and Risks
Risks include nasopharyngitis, headache, joint pain and rare pancreatitis. Handle with enzyme‑inhibitor precautions.
Datasheet
| Molecular Formula | C14H26BN3O9 |
|---|---|
| Molecular Weight | 391.18 g/mol |
| CAS Number | 890402-81-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Dutogliptin tartrate; 890402-81-0; Dutogliptin tartrate [USAN]; UNII-79QH89EV9M; 79QH89EV9M |
| IUPAC/Chemical Name | (2R,3R)-2,3-dihydroxybutanedioic acid;[(2R)-1-[2-[[(3R)-pyrrolidin-3-yl]amino]acetyl]pyrrolidin-2-yl]boronic acid |
| InChl Key | SVWHNLVZPGXBNS-MHDNXTQBSA-N |
| InChl Code | InChI=1S/C10H20BN3O3.C4H6O6/c15-10(7-13-8-3-4-12-6-8)14-5-1-2-9(14)11(16)17;5-1(3(7)8)2(6)4(9)10/h8-9,12-13,16-17H,1-7H2;1-2,5-6H,(H,7,8)(H,9,10)/t8-,9+;1-,2-/m11/s1 |
| References |
3D Conformer.
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