About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Dutogliptin is a selective DPP4 inhibitor that prevents degradation of incretin hormones (GLP1, GIP). This prolongs insulinotropic signalling, enhances glucosedependent insulin release and suppresses inappropriate glucagon secretion.
Benefits and Advantages
Used in incretinpathway modulation studies, DPP4 inhibition assays, glucoseregulation modelling, and combinationtherapy research with GLP1 agonists.
Side Effects and Risks
Risks include nasopharyngitis, headache, joint pain and rare pancreatitis. Handle with enzymeinhibitor precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C14H26BN3O9 |
|---|---|
| Molecular Weight | 391.18 g/mol |
| CAS Number | 890402-81-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Dutogliptin tartrate; 890402-81-0; Dutogliptin tartrate [USAN]; UNII-79QH89EV9M; 79QH89EV9M |
| IUPAC/Chemical Name | (2R,3R)-2,3-dihydroxybutanedioic acid;[(2R)-1-[2-[[(3R)-pyrrolidin-3-yl]amino]acetyl]pyrrolidin-2-yl]boronic acid |
| InChl Key | SVWHNLVZPGXBNS-MHDNXTQBSA-N |
| InChl Code | InChI=1S/C10H20BN3O3.C4H6O6/c15-10(7-13-8-3-4-12-6-8)14-5-1-2-9(14)11(16)17;5-1(3(7)8)2(6)4(9)10/h8-9,12-13,16-17H,1-7H2;1-2,5-6H,(H,7,8)(H,9,10)/t8-,9+;1-,2-/m11/s1 |
| References |
3D Conformer.
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