About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Dutasteride is a dual 5reductase inhibitor (types 1 and 2), blocking conversion of testosterone to dihydrotestosterone (DHT). This reduces androgenic signalling in prostate tissue, hair follicles and sebaceous glands. It lowers DHT levels more profoundly than finasteride.
Benefits and Advantages
Used in androgenpathway studies, prostatebiology modelling, hairfollicle miniaturization research, and endocrineaxis inhibition assays.
Side Effects and Risks
Risks include decreased libido, gynecomastia, erectile changes and potential reproductive effects. Handle with potent androgenmodulator precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C27H30F6N2O2 |
|---|---|
| Molecular Weight | 528.5 g/mol |
| CAS Number | 164656-23-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Insoluble |
| Purity | Purity information is available upon request (COA). |
| Synonym | Dutasteride; 164656-23-9; Avodart; Avolve; GG-745 |
| IUPAC/Chemical Name | (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide |
| InChl Key | JWJOTENAMICLJG-QWBYCMEYSA-N |
| InChl Code | InChI=1S/C27H30F6N2O2/c1-24-11-9-17-15(4-8-21-25(17,2)12-10-22(36)35-21)16(24)6-7-19(24)23(37)34-20-13-14(26(28,29)30)3-5-18(20)27(31,32)33/h3,5,10,12-13,15-17,19,21H,4,6-9,11H2,1-2H3,(H,34,37)(H,35,36)/t15-,16-,17-,19+,21+,24-,25+/m0/s1 |
| References |
3D Conformer.
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