DYCLONINE
Dyclonine is a topical anesthetic blocking sodium channels to reduce throat and mucosal pain. Side effects include numbness, mild irritation, and rare allergic reactions. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Dyclonine is a topical anesthetic that blocks voltagegated sodium channels in sensory neurons, inhibiting depolarization and preventing actionpotential propagation. It provides localized analgesia without structural relation to amide or ester anesthetics.
Benefits and Advantages
Used in sodiumchannel pharmacology, peripheralnerve blockade studies, topical anesthetic SAR research, and sensorynerve conduction modelling.
Side Effects and Risks
Risks include mucosal irritation, numbness, hypersensitivity, CNS excitation at high doses and methemoglobinemia (rare). Handle with localanesthetic precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C18H27NO2 |
|---|---|
| Molecular Weight | 289.4 g/mol |
| CAS Number | 586-60-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Soluble (HCl salt) |
| Purity | Purity information is available upon request (COA). |
| Synonym | dyclonine; Dyclocaine; 586-60-7; Diclonina; Dycloninum |
| IUPAC/Chemical Name | 1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one |
| InChl Key | BZEWSEKUUPWQDQ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H27NO2/c1-2-3-15-21-17-9-7-16(8-10-17)18(20)11-14-19-12-5-4-6-13-19/h7-10H,2-6,11-15H2,1H3 |
| References |
3D Conformer.
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