DOPAMINE HCL
Dopamine HCl is a catecholamine used to support cardiac output and renal perfusion by stimulating dopaminergic and adrenergic receptors. Side effects include arrhythmias, hypertension, and tissue necrosis with extravasation. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Dopamine hydrochloride is an endogenous catecholamine used as a pharmacologic agonist at dopaminergic, adrenergic and adrenergic receptors in a dosedependent manner. Low doses stimulate D receptors and renal vasodilation; intermediate doses enhance contractility via activity; high doses induce vasoconstriction through activation.
Benefits and Advantages
Used in receptorselectivity modelling, cardiovascular pharmacology, renalhemodynamics studies, catecholamine signalling assays and doseresponse gradient research.
Side Effects and Risks
Risks include tachyarrhythmias, hypertension, ischemia, extravasation injury, metabolic acidosis and tissue necrosis. Handle with potent catecholamine precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C8H11NO2·HCl |
|---|---|
| Molecular Weight | 189.64 g/mol |
| CAS Number | 62-31-7 |
| Storage Condition | Some commercially available injections of dopamine in dextrose provided in plastic containers should be stored at room temperature (25 °C), although brief exposure to temperatures up to 40 °C does not adversely affect the injections; the injections should be protected from excessive heat and should not be frozen.. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Dopamine hydrochloride; 62-31-7; Dopamine HCl; Cardiosteril; 1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride |
| IUPAC/Chemical Name | 4-(2-aminoethyl)benzene-1,2-diol;hydrochloride |
| InChl Key | CTENFNNZBMHDDG-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C8H11NO2.ClH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H |
| References |
3D Conformer.
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