About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Domagrozumab is a humanized monoclonal antibody that binds myostatin (GDF8), a TGF family cytokine that negatively regulates muscle growth. By neutralizing myostatin, domagrozumab enhances muscle fibre size, increases satellitecell activity and promotes hypertrophy. It modulates SMAD2/3 signalling and counteracts catabolic gene expression.
Benefits and Advantages
Used in muscleregeneration research, Duchenne muscular dystrophy modelling, myostatinpathway inhibition assays, SMADsignalling studies and anabolictherapeutic development.
Side Effects and Risks
Risks include injectionsite reactions, immune responses, muscle enzyme elevation and unknown longterm metabolic effects. Handle with monoclonalantibody precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | Protein |
|---|---|
| Molecular Weight | 150000.0 g/mol |
| CAS Number | 1393551-88-2 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| IUPAC/Chemical Name | Monoclonal antibody |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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