About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Dipivefrin hydrochloride is a prodrug of epinephrine in which epinephrine is esterified with pivalic acid. The increased lipophilicity enhances corneal penetration; intraocular esterases then release epinephrine, which activates and adrenergic receptors in the eye. This reduces intraocular pressure by decreasing aqueous humour production and increasing outflow.
Benefits and Advantages
Used in ophthalmic pharmacology research, adrenergicreceptor pathway studies, prodrugactivation assays, and glaucomamodel investigations.
Side Effects and Risks
Risks include ocular irritation, burning, conjunctival hyperemia, systemic sympathomimetic effects (tachycardia, hypertension) and rare arrhythmias. Handle with adrenergicprodrug and ocularagent precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C19H29NO5·HCl |
|---|---|
| Molecular Weight | 387.9 g/mol |
| CAS Number | 64019-93-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Dipivefrin hydrochloride; 64019-93-8; Dipivefrin HCL; Dipivefrine hydrochloride; AKPro |
| IUPAC/Chemical Name | [2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate;hydrochloride |
| InChl Key | VKFAUCPBMAGVRG-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C19H29NO5.ClH/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6;/h8-10,13,20-21H,11H2,1-7H3;1H |
| References |
3D Conformer.
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