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Product Description
Mechanism of Action
Diprophylline (dyphylline) is a theophylline derivative with bronchodilator and mild diuretic properties. It inhibits phosphodiesterase, leading to increased intracellular cAMP, relaxation of bronchial smooth muscle and improved airflow. It also antagonizes adenosine receptors, contributing to bronchodilation and CNS stimulation with reduced potency compared to theophylline.
Benefits and Advantages
Used in bronchodilationmechanism research, PDEinhibition studies, adenosinereceptor pathway modelling, and xanthine SAR investigations.
Side Effects and Risks
Risks include tachycardia, CNS stimulation (insomnia, tremor), GI upset and arrhythmias at high concentrations. Handle with xanthineclass bronchodilator precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C10H14N4O4 |
|---|---|
| Molecular Weight | 254.24 g/mol |
| CAS Number | 479-18-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | dyphylline; Diprophylline; 479-18-5; Diphylline; 7-(2,3-Dihydroxypropyl)theophylline |
| IUPAC/Chemical Name | 7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione |
| InChl Key | KSCFJBIXMNOVSH-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3 |
| References |
3D Conformer.
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