DIMETHINDENE MALEATE
Dimethindene maleate is an H1 antihistamine used for allergies and itching. Benefits include rapid symptom relief. Side effects include drowsiness, dry mouth, and mild dizziness. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Dimethindene maleate is a selective Hhistaminereceptor antagonist with additional anticholinergic activity. It reduces vascular permeability, pruritus and allergic inflammation. It crosses the bloodbrain barrier but exhibits moderate sedation relative to firstgeneration antihistamines.
Benefits and Advantages
Used in histaminepathway studies, allergymodelling research, Hreceptor antagonism assays, and inflammatorymediator analysis.
Side Effects and Risks
Risks include drowsiness, dry mouth, dizziness, urinary retention and anticholinergic effects. Handle with antihistamineclass precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C20H24N2·C4H4O4 |
|---|---|
| Molecular Weight | 408.5 g/mol |
| CAS Number | 3614-69-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Dimethindene maleate; 3614-69-5; Dimetindene maleate; Forhistal maleate; Dimethpyrindene maleate |
| IUPAC/Chemical Name | (Z)-but-2-enedioic acid;N,N-dimethyl-2-[3-(1-pyridin-2-ylethyl)-1H-inden-2-yl]ethanamine |
| InChl Key | SWECWXGUJQLXJF-BTJKTKAUSA-N |
| InChl Code | InChI=1S/C20H24N2.C4H4O4/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20;5-3(6)1-2-4(7)8/h4-10,12,15H,11,13-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1- |
| References |
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