DIMERCAPTOSUCCINIC ACID
Dimercaptosuccinic acid (DMSA) is an oral chelator removing lead and other metals with improved safety. Benefits include reduced toxicity with minimal side effects such as GI upset or rash.
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Product Description
Mechanism of Action
Dimercaptosuccinic acid (DMSA) is an oral heavy‑metal chelator with two thiol groups that bind lead, mercury and arsenic. It forms stable, water‑soluble complexes eliminated via urine. It does not significantly chelate essential minerals, making it safer than BAL.
Benefits and Advantages
Used in heavy‑metal exposure modelling, chelation‑efficacy assays, toxicology studies, and succinic‑acid thiol‑reactivity research.
Side Effects and Risks
Risks include nausea, rash, elevated liver enzymes, neutropenia and sulfur‑related odor. Handle with thiol‑chelating‑agent precautions.
Datasheet
| Molecular Formula | C4H6O4S2 |
|---|---|
| Molecular Weight | 182.2 g/mol |
| CAS Number | 2418-14-6 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | 2.43e+00 g/L |
| Purity | Purity information is available upon request (COA). |
| Synonym | 2,3-Dimercaptosuccinic acid; Dimercaptosuccinic acid; 2418-14-6; Suximer; 2,3-Dimercaptobutanedioic acid |
| IUPAC/Chemical Name | 2,3-bis(sulfanyl)butanedioic acid |
| InChl Key | ACTRVOBWPAIOHC-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C4H6O4S2/c5-3(6)1(9)2(10)4(7)8/h1-2,9-10H,(H,5,6)(H,7,8) |
| References |
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