DIMERCAPTOSUCCINIC ACID

Dimercaptosuccinic acid (DMSA) is an oral chelator removing lead and other metals with improved safety. Benefits include reduced toxicity with minimal side effects such as GI upset or rash.

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Product Description


Mechanism of Action

Dimercaptosuccinic acid (DMSA) is an oral heavy‑metal chelator with two thiol groups that bind lead, mercury and arsenic. It forms stable, water‑soluble complexes eliminated via urine. It does not significantly chelate essential minerals, making it safer than BAL.

Benefits and Advantages

Used in heavy‑metal exposure modelling, chelation‑efficacy assays, toxicology studies, and succinic‑acid thiol‑reactivity research.

Side Effects and Risks

Risks include nausea, rash, elevated liver enzymes, neutropenia and sulfur‑related odor. Handle with thiol‑chelating‑agent precautions.

Datasheet


Molecular Formula

C4H6O4S2

Molecular Weight

182.2 g/mol

CAS Number

2418-14-6

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

2.43e+00 g/L

Purity

Purity information is available upon request (COA).

Synonym

2,3-Dimercaptosuccinic acid; Dimercaptosuccinic acid; 2418-14-6; Suximer; 2,3-Dimercaptobutanedioic acid

IUPAC/Chemical Name

2,3-bis(sulfanyl)butanedioic acid

InChl Key

ACTRVOBWPAIOHC-UHFFFAOYSA-N

InChl Code

InChI=1S/C4H6O4S2/c5-3(6)1(9)2(10)4(7)8/h1-2,9-10H,(H,5,6)(H,7,8)

References

https://pubchem.ncbi.nlm.nih.gov/compound/9354;

3D Conformer.

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