DICYCLOVERINE
Dicycloverine is an anticholinergic that relaxes intestinal smooth muscle, easing cramping. Side effects include constipation, dry mouth, and drowsiness. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Dicycloverine (dicycloverine hydrochloride) is an antimuscarinic antispasmodic that inhibits acetylcholine binding at Mreceptors on GI smooth muscle. It decreases intestinal motility, spasms and secretions. It has a similar mechanism to dicyclomine with both central and peripheral anticholinergic effects.
Benefits and Advantages
Used in muscarinicsignalling research, GI spasm modelling, cholinergicreceptor pharmacology, and visceral hypersensitivity studies.
Side Effects and Risks
Risks include tachycardia, blurred vision, cognitive impairment, urinary retention and anticholinergic toxicity at high doses. Handle under anticholinergicagent precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C19H35NO2 |
|---|---|
| Molecular Weight | 309.5 g/mol |
| CAS Number | 77-19-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | SOL IN WATER ABOUT 25% /HYDROCHLORIDE/ |
| Purity | Purity information is available upon request (COA). |
| Synonym | dicyclomine; Dicycloverine; Dicycloverin; 77-19-0; Diocyl |
| IUPAC/Chemical Name | 2-(diethylamino)ethyl 1-cyclohexylcyclohexane-1-carboxylate |
| InChl Key | CURUTKGFNZGFSE-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3 |
| References |
3D Conformer.
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