About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of action
Benoxaprofen is an arylpropionic-acid NSAID that inhibits cyclooxygenase (COX-1 and COX-2), reducing prostaglandin synthesis and exerting anti-inflammatory, analgesic and antipyretic effects. It also exhibits peroxisome-proliferator activation and photosensitising properties.
Benefits and advantages
Used in inflammatory-pathway research, prostaglandin biosynthesis modelling, photoactivation studies, oxidative stress analysis and pharmacovigilance evaluations of hepatotoxicity mechanisms.
Side effects and risks
Risks include severe hepatotoxicity, photosensitivity, GI toxicity and renal impairment. Must be handled with NSAID-active and photoreactive-compound precautions.
Datasheet
| Molecular Formula | C16H12ClNO3 |
|---|---|
| Molecular Weight | 301.72 g/mol |
| CAS Number | 51234-28-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Benoxaprofen; 51234-28-7; Oraflex; Coxigon; Opren |
| IUPAC/Chemical Name | 2-[2-(4-chlorophenyl)-1,3-benzoxazol-5-yl]propanoic acid |
| InChl Key | MITFXPHMIHQXPI-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C16H12ClNO3/c1-9(16(19)20)11-4-7-14-13(8-11)18-15(21-14)10-2-5-12(17)6-3-10/h2-9H,1H3,(H,19,20) |
| References |
3D Conformer.
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