BENOXINATE HYDROCHLORIDE

Benoxinate hydrochloride is a topical anesthetic used in ophthalmology to numb the cornea. Benefits include rapid onset. Side effects include temporary stinging and rare allergic reactions. Only GMP materials will be supplied, logistics all according to GDP.

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Product Description


Mechanism of action

Benoxinate HCl is an ester-type local anaesthetic that blocks voltage-gated sodium channels in sensory nerves, preventing action potential initiation and propagation. It is primarily used in ophthalmic anaesthesia.

Benefits and advantages

Used in ocular pharmacology, corneal nerve-mapping studies, anaesthetic penetration research and sodium-channel physiology experiments. Its rapid onset makes it useful for short-duration sensory-block modelling.

Side effects and risks

Risks include corneal irritation, allergic reactions, CNS toxicity upon systemic absorption and potential cardiac depression at high exposure levels. Handle under local-anaesthetic safety protocols.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C17H29ClN2O3

Molecular Weight

344.9 g/mol

CAS Number

5987-82-6

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Very soluble (hydrochloride salt)

Purity

Purity information is available upon request (COA).

Synonym

Benoxinate hydrochloride; 5987-82-6; oxybuprocaine hydrochloride; Oxybuprocaine HCL; Benoxinate HCL

IUPAC/Chemical Name

2-(diethylamino)ethyl 4-amino-3-butoxybenzoate;hydrochloride

InChl Key

PRGUDWLMFLCODA-UHFFFAOYSA-N

InChl Code

InChI=1S/C17H28N2O3.ClH/c1-4-7-11-21-16-13-14(8-9-15(16)18)17(20)22-12-10-19(5-2)6-3;/h8-9,13H,4-7,10-12,18H2,1-3H3;1H

References

https://pubchem.ncbi.nlm.nih.gov/compound/6420040;

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