BENFURODIL

Benfurodil is a vasodilator improving coronary and peripheral blood flow. Benefits include reduced angina symptoms. Side effects may include dizziness, flushing, and hypotension. Only GMP materials will be supplied, logistics all according to GDP.

SKU: fd712d73db53 Category: Tag:

Product Description


Mechanism of action

Benfurodil is a vasodilator with calcium-channelblocking activity, reducing calcium influx in vascular smooth muscle and thereby decreasing peripheral vascular resistance. It also exhibits mild PDE inhibition and antiplatelet effects.

Benefits and advantages

Useful in vascular pharmacology, microcirculation research, smooth-muscle contractility studies, endothelial function investigations and dual-mode vasodilator modelling.

Side effects and risks

Potential risks include dizziness, flushing, hypotension, palpitations and mild GI upset. Requires vascular-active safety handling.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C15H14O4

Molecular Weight

258.27 g/mol

CAS Number

3448-13-3

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Benfurodil; 3448-13-3; 71DV8DHP4B; RefChem:912043; 4-(2-(1-Hydroxyethyl)-3-methyl-5-benzofuranyl)-2(5H)-furanone

IUPAC/Chemical Name

3-[2-(1-hydroxyethyl)-3-methyl-1-benzofuran-5-yl]-2H-furan-5-one

InChl Key

MQNWWJVIEQBJJO-UHFFFAOYSA-N

InChl Code

InChI=1S/C15H14O4/c1-8-12-5-10(11-6-14(17)18-7-11)3-4-13(12)19-15(8)9(2)16/h3-6,9,16H,7H2,1-2H3

References

https://pubchem.ncbi.nlm.nih.gov/compound/103014;

3D Conformer.

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