About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Ethosuximide is an antiabsenceseizure medication that selectively inhibits Ttype calcium channels in thalamic neurons. By reducing thalamocortical oscillations, it prevents the spikeandwave discharges characteristic of absence epilepsy.
Benefits and Advantages
Used in Ttype calciumchannel studies, seizurecircuit modelling, thalamocortical rhythm research, and antiepilepticdrug mechanism assays.
Side Effects and Risks
Risks include GI upset, fatigue, headache, blood dyscrasias and rare StevensJohnson syndrome. Handle with CNSactive antiepileptic precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C7H11NO4 |
|---|---|
| Molecular Weight | 141.17 g/mol |
| CAS Number | 77-67-8 |
| Storage Condition | Ethosuximide capsules should be stored in tight containers at a temperature less than 30 °C, preferably between 15-30 °C. Ethosuximide oral solution should be stored in tight, light-resistant containers at a temperature less than 30 °C, preferably between 15-30 °C; freezing should be avoided. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | ethosuximide; 77-67-8; Zarontin; Etosuximida; 2-Ethyl-2-methylsuccinimide |
| IUPAC/Chemical Name | 3-ethyl-3-methylpyrrolidine-2,5-dione |
| InChl Key | HAPOVYFOVVWLRS-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10) |
| References |
3D Conformer.
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