About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Ethosuximide is an anti‑absence‑seizure medication that selectively inhibits T‑type calcium channels in thalamic neurons. By reducing thalamocortical oscillations, it prevents the spike‑and‑wave discharges characteristic of absence epilepsy.
Benefits and Advantages
Used in T‑type calcium‑channel studies, seizure‑circuit modelling, thalamocortical rhythm research, and antiepileptic‑drug mechanism assays.
Side Effects and Risks
Risks include GI upset, fatigue, headache, blood dyscrasias and rare Stevens–Johnson syndrome. Handle with CNS‑active antiepileptic precautions.
Datasheet
| Molecular Formula | C7H11NO4 |
|---|---|
| Molecular Weight | 141.17 g/mol |
| CAS Number | 77-67-8 |
| Storage Condition | Ethosuximide capsules should be stored in tight containers at a temperature less than 30 °C, preferably between 15-30 °C. Ethosuximide oral solution should be stored in tight, light-resistant containers at a temperature less than 30 °C, preferably between 15-30 °C; freezing should be avoided. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | ethosuximide; 77-67-8; Zarontin; Etosuximida; 2-Ethyl-2-methylsuccinimide |
| IUPAC/Chemical Name | 3-ethyl-3-methylpyrrolidine-2,5-dione |
| InChl Key | HAPOVYFOVVWLRS-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10) |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
