About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Epoprostenol (prostacyclin, PGI₂) is a potent vasodilator and inhibitor of platelet aggregation. It activates the IP receptor, stimulating adenylate cyclase, increasing intracellular cAMP and relaxing vascular smooth muscle. It counteracts thromboxane‑mediated vasoconstriction and thrombosis.
Benefits and Advantages
Used in pulmonary‑hypertension models, platelet‑aggregation inhibition studies, vascular‑tone signalling assays, and prostaglandin‑pathway research.
Side Effects and Risks
Risks include hypotension, flushing, jaw pain, headache, bleeding, rebound pulmonary hypertension and infusion‑site instability. Handle with potent prostaglandin‑agonist precautions.
Datasheet
| Molecular Formula | C20H31NaO5 |
|---|---|
| Molecular Weight | 374.4 g/mol |
| CAS Number | 61849-14-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Epoprostenol sodium; 61849-14-7; Cyclo-Prostin; Sodium prostacyclin; Prostacyclin sodium salt |
| IUPAC/Chemical Name | sodium (5Z)-5-[(3aR,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoate |
| InChl Key | LMHIPJMTZHDKEW-XQYLJSSYSA-M |
| InChl Code | InChI=1S/C20H32O5.Na/c1-2-3-4-7-14(21)10-11-16-17-12-15(8-5-6-9-20(23)24)25-19(17)13-18(16)22;/h8,10-11,14,16-19,21-22H,2-7,9,12-13H2,1H3,(H,23,24);/q;+1/p-1/b11-10+,15-8-;/t14-,16+,17+,18+,19-;/m0./s1 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
