DOPAMINE HCL

Dopamine HCl is a catecholamine used to support cardiac output and renal perfusion by stimulating dopaminergic and adrenergic receptors. Side effects include arrhythmias, hypertension, and tissue necrosis with extravasation. Only GMP materials will be supplied, logistics all according to GDP.

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Product Description


Mechanism of Action

Dopamine hydrochloride is an endogenous catecholamine used as a pharmacologic agonist at dopaminergic, adrenergic and adrenergic receptors in a dosedependent manner. Low doses stimulate D receptors and renal vasodilation; intermediate doses enhance contractility via activity; high doses induce vasoconstriction through activation.

Benefits and Advantages

Used in receptorselectivity modelling, cardiovascular pharmacology, renalhemodynamics studies, catecholamine signalling assays and doseresponse gradient research.

Side Effects and Risks

Risks include tachyarrhythmias, hypertension, ischemia, extravasation injury, metabolic acidosis and tissue necrosis. Handle with potent catecholamine precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C8H11NO2·HCl

Molecular Weight

189.64 g/mol

CAS Number

62-31-7

Storage Condition

Some commercially available injections of dopamine in dextrose provided in plastic containers should be stored at room temperature (25 °C), although brief exposure to temperatures up to 40 °C does not adversely affect the injections; the injections should be protected from excessive heat and should not be frozen..

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Dopamine hydrochloride; 62-31-7; Dopamine HCl; Cardiosteril; 1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride

IUPAC/Chemical Name

4-(2-aminoethyl)benzene-1,2-diol;hydrochloride

InChl Key

CTENFNNZBMHDDG-UHFFFAOYSA-N

InChl Code

InChI=1S/C8H11NO2.ClH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H

References

https://pubchem.ncbi.nlm.nih.gov/compound/65340;

3D Conformer.

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