About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Ciprofloxacin hydrochloride is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV. By stabilizing the enzyme–DNA cleavage complex, it prevents DNA supercoiling, replication and chromosomal separation, ultimately producing lethal double-strand DNA breaks. The HCl salt improves solubility and aqueous stability.
Benefits and Advantages
Used in DNA-gyrase pathway research, fluoroquinolone resistance modelling (QRDR mutations), PK/PD simulation studies, biofilm-penetration research, gram-negative susceptibility assays and medicinal-chemistry salt optimization.
Side Effects and Risks
Risks include tendon rupture, neuropathy, QT prolongation, CNS excitation, phototoxicity, dysglycemia and hepatotoxicity. Handle with fluoroquinolone-class precautions.
Datasheet
| Molecular Formula | C17H19ClFN3O3 |
|---|---|
| Molecular Weight | 367.8 g/mol |
| CAS Number | 86483-48-9 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | 86393-32-0; Ciloxan; Ciprofloxacin hydrochloride hydrate; Ciprofloxacin hydrochloride monohydrate; Ciprofloxacin HCl |
| IUPAC/Chemical Name | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)quinoline-3-carboxylic acid hydrochloride |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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