CIPROFLOXACINE BASE
Ciprofloxacin hydrochloride provides the same antibacterial mechanism in salt form. Side effects include nausea, dizziness, and hypersensitivity. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Ciprofloxacin base is the nonsalt, freebase form of ciprofloxacin with identical mechanisms: inhibition of bacterial DNA gyrase and topoisomerase IV, resulting in lethal disruption of DNA replication and repair. The base form is used in medicinalchemistry optimisation and solubilityprofile analysis.
Benefits and Advantages
Used in physicochemicalproperty studies, freebase/salt comparison research, fluoroquinolone SAR work, gyrasebinding analysis and formulation development.
Side Effects and Risks
Risks mirror ciprofloxacin salts: tendinopathy, neuropathy, CNS stimulation, hepatotoxicity and phototoxicity. Handle with quinolonecompound precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C17H18FN3O3 |
|---|---|
| Molecular Weight | 315.34 g/mol |
| CAS Number | 85721-33-1 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | ciprofloxacin; 85721-33-1; Ciprofloxacine; Ciprobay; Cipro |
| IUPAC/Chemical Name | 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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