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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Product Description
Mechanism of action
Carvedilol is a non‑selective β‑adrenergic antagonist with additional α₁‑receptor blocking activity. It reduces cardiac workload through β₁ blockade while producing vasodilation via α₁ antagonism. Carvedilol also exhibits antioxidant properties and modulates mitochondrial dysfunction in cardiomyocytes.
Benefits and advantages
Used in heart‑failure research, hypertension studies, adrenergic‑receptor signalling research, oxidative‑stress cardiac models, vascular‑remodelling studies and β/α‑mixed antagonist SAR investigations.
Side effects and risks
Risks include hypotension, dizziness, bradycardia, fatigue, bronchospasm and metabolic disturbances. Handle with cardiovascular‑active compound precautions.
Datasheet
| Molecular Formula | C24H26N2O4 |
|---|---|
| Molecular Weight | 406.5 g/mol |
| CAS Number | 72956-09-3 |
| Storage Condition | Store in tight container as defined in the USP-NF. This material should be handled and stored per label instructions to ensure product integrity. |
| Solubility | 88mg/mL |
| Purity | Purity information is available upon request (COA). |
| Synonym | carvedilol; 72956-09-3; Coreg; Dilatrend; Eucardic |
| IUPAC/Chemical Name | 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol |
| InChl Key | OGHNVEJMJSYVRP-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C24H26N2O4/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20/h2-12,17,25-27H,13-16H2,1H3 |
| References |
3D Conformer.
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