About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of action
Boldine is an aporphine alkaloid with antioxidant, anti-inflammatory, hepatoprotective and cholinesteraseinhibitory properties. It modulates oxidativestress pathways by scavenging reactive oxygen species, stabilising mitochondrial membranes and influencing glutathione metabolism. Boldine also exhibits cholinergic and vasodilatory activity.
Benefits and advantages
Used in oxidativestress research, hepaticprotection models, neuroprotection studies, cholinesteraseinhibitor screening, vascularbiology investigations and plantalkaloid SAR research.
Side effects and risks
Risks include mild GI discomfort, cholinergic effects at high doses, hepatic enzyme alteration and rare allergic reactions. Handle as a bioactive phytochemical.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C19H21NO4 |
|---|---|
| Molecular Weight | 327.4 g/mol |
| CAS Number | 476-70-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Boldine; 476-70-0; (S)-Boldine; (+)-Boldine; 1,10-Dimethoxy-2,9-dihydroxyaporphine |
| IUPAC/Chemical Name | (6aS)-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol |
| InChl Key | LZJRNLRASBVRRX-ZDUSSCGKSA-N |
| InChl Code | InChI=1S/C19H21NO4/c1-20-5-4-10-7-15(22)19(24-3)18-12-9-16(23-2)14(21)8-11(12)6-13(20)17(10)18/h7-9,13,21-22H,4-6H2,1-3H3/t13-/m0/s1 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
