About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Droperidol is a dopamine D₂‑receptor antagonist with antiemetic, antipsychotic and sedative properties. It blocks dopaminergic signalling in the chemoreceptor trigger zone and has α‑adrenergic and serotonergic modulation effects. Its rapid onset makes it valuable in CNS behavioural‑research and antiemetic assays.
Benefits and Advantages
Used in dopamine‑pathway research, antiemetic mechanism studies, sedation modelling, and neuroreceptor pharmacology assays.
Side Effects and Risks
Risks include QT prolongation, extrapyramidal symptoms, hypotension, akathisia, and CNS depression. Handle with antipsychotic/antiemetic precautions.
Datasheet
| Molecular Formula | C22H22FN3O2 |
|---|---|
| Molecular Weight | 379.4 g/mol |
| CAS Number | 548-73-2 |
| Storage Condition | Commercially available droperidol injection should be protected from light and stored at room temperature (15-25 °C). |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | droperidol; 548-73-2; Droleptan; Inapsine; Dehydrobenzperidol |
| IUPAC/Chemical Name | 3-[1-[4-(4-fluorophenyl)-4-oxobutyl]-3,6-dihydro-2H-pyridin-4-yl]-1H-benzimidazol-2-one |
| InChl Key | RMEDXOLNCUSCGS-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C22H22FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-11H,3,6,12-15H2,(H,24,28) |
| References |
3D Conformer.
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