FLUDARIBINE

Fludarabine is a purine analogue used in leukemia, inhibiting DNA synthesis. Side effects include severe immunosuppression, anemia, and neurotoxicity. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 9a9d1dc6ada3 Category: Tag:

Product Description


Mechanism of Action

Fludarabine is a purine nucleoside analogue that inhibits DNA polymerase, ribonucleotide reductase and DNA primase, inducing apoptosis in lymphoid cells.

Benefits and Advantages

Used in hematologic malignancy modelling, purinepathway inhibition assays and apoptosismechanism studies.

Side Effects and Risks

Risks include severe immunosuppression, neurotoxicity and myelosuppression.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C10H13FN5O4

Molecular Weight

285.24 g/mol

CAS Number

75607-67-9

Storage Condition

Store in a cool, dry place; protect from light

Solubility

Soluble in water

Purity

Purity information is available upon request (COA).

Synonym

2-fluoro-9-(5-o-phosphonopentofuranosyl)-9h-purin-6-amine; FAMP; C10H13FN5O7P; Fludarabine Phosphate (Fludara); Fludura

IUPAC/Chemical Name

9H-purin-6-amine, 2-fluoro-9-(5-oxopentyl)

InChl Key

Unavailable

InChl Code

Unavailable

References

PubChem; ChemBL; FDA;

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