ELEDOISIN

Eledoisin is a peptide that induces vasodilation and smooth muscle contraction, used in research. Side effects involve flushing, hypotension, and localized reactions. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 095f64c1711a Category: Tag:

Product Description


Mechanism of Action

Eledoisin is a tachykinin neuropeptide (related to substance P) that activates NK, NK and NK receptors, producing vasodilation, smoothmuscle contraction and painsignal transmission. It is isolated from cephalopod venom and used as a neuropeptide model compound.

Benefits and Advantages

Used in tachykininreceptor research, neurogenicinflammation studies, smoothmuscle physiology, and nociceptivepathway assays.

Side Effects and Risks

Risks include vasodilation, flushing, bronchoconstriction, hypotension and strong nociceptive stimulation. Handle with neuropeptideactive substance precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C54H85N13O15S

Molecular Weight

1188.4 g/mol

CAS Number

69-25-0

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

ELEDOISIN; Eledone peptide; 69-25-0; Eledoisina; Eledoisine

IUPAC/Chemical Name

(3S)-3-[[(2S)-6-amino-2-[[(2S)-3-hydroxy-2-[[(2S)-1-[(2S)-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]hexanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid

InChl Key

AYLPVIWBPZMVSH-FCKMLYJASA-N

InChl Code

InChI=1S/C54H85N13O15S/c1-7-30(4)44(53(81)57-27-42(70)60-36(24-29(2)3)49(77)61-33(45(56)73)20-23-83-6)66-50(78)37(25-32-14-9-8-10-15-32)63-46(74)31(5)58-48(76)38(26-43(71)72)64-47(75)34(16-11-12-21-55)62-51(79)39(28-68)65-52(80)40-17-13-22-67(40)54(82)35-18-19-41(69)59-35/h8-10,14-15,29-31,33-40,44,68H,7,11-13,16-28,55H2,1-6H3,(H2,56,73)(H,57,81)(H,58,76)(H,59,69)(H,60,70)(H,61,77)(H,62,79)(H,63,74)(H,64,75)(H,65,80)(H,66,78)(H,71,72)/t30-,31-,33-,34-,35-,36-,37-,38-,39-,40-,44-/m0/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/10328936;

3D Conformer.

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