BETULOL

Betulol is a plant-derived compound with reported antioxidant and vasoprotective effects. Side effects are minimal but may include mild headache or GI discomfort. Only GMP materials will be supplied, logistics all according to GDP.

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Product Description


Mechanism of action

Betulol is a semisynthetic triterpenoid structurally related to betulin, exhibiting antiinflammatory, antioxidant and vasodilatory properties. Mechanistically, it modulates nitricoxide signalling, reduces oxidative stress and may influence eicosanoid pathways.

Benefits and advantages

Used in vascularbiology studies, inflammation models, oxidativestress research, nitricoxidepathway investigations and structuremodification screens of triterpenoid derivatives.

Side effects and risks

Risks include mild cytotoxicity at higher doses, hepatic enzyme elevation and irritation. Handle with plantderived triterpenoid compound precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C30H50O2

Molecular Weight

442.7 g/mol

CAS Number

473-98-3

Storage Condition

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Solubility

greater than or equal to 100 mg/mL at 70 °F (NTP, 1992)

Purity

Purity information is available upon request (COA).

Synonym

Betulin; 473-98-3; Betulinol; Trochol; Betuline

IUPAC/Chemical Name

(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-(hydroxymethyl)-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol

InChl Key

FVWJYYTZTCVBKE-ROUWMTJPSA-N

InChl Code

InChI=1S/C30H50O2/c1-19(2)20-10-15-30(18-31)17-16-28(6)21(25(20)30)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h20-25,31-32H,1,8-18H2,2-7H3/t20-,21+,22-,23+,24-,25+,27-,28+,29+,30+/m0/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/72326;

3D Conformer.

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