ESTRADIOL VALERATE
Estradiol valerate is a long‑acting estrogen ester used for HRT and contraception. Side effects include breast swelling, nausea, and increased clot risk.
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Product Description
Mechanism of Action
Estradiol valerate is a prodrug ester slowly hydrolyzed to estradiol, providing sustained estrogenic signalling. It activates estrogen receptors to regulate reproductive physiology, bone homeostasis and metabolic pathways.
Benefits and Advantages
Used in depot‑estrogen pharmacology, ER‑signalling research, hormone‑replacement modelling, and controlled‑release formulation development.
Side Effects and Risks
Risks include thromboembolism, breast tenderness, nausea and hepatic stimulation. Handle with estrogen‑ester precautions.
Datasheet
| Molecular Formula | C23H32O3 |
|---|---|
| Molecular Weight | 356.5 g/mol |
| CAS Number | 979-32-8 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | estradiol valerate; 979-32-8; Estradiol 17-valerate; Delestrogen; Climaval |
| IUPAC/Chemical Name | [(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] pentanoate |
| InChl Key | RSEPBGGWRJCQGY-RBRWEJTLSA-N |
| InChl Code | InChI=1S/C23H32O3/c1-3-4-5-22(25)26-21-11-10-20-19-8-6-15-14-16(24)7-9-17(15)18(19)12-13-23(20,21)2/h7,9,14,18-21,24H,3-6,8,10-13H2,1-2H3/t18-,19-,20+,21+,23+/m1/s1 |
| References |
3D Conformer.
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