ESTRADIOL VALERATE

Estradiol valerate is a long‑acting estrogen ester used for HRT and contraception. Side effects include breast swelling, nausea, and increased clot risk.

SKU: 07e8199cf50d Category: Tag:

Product Description


Mechanism of Action

Estradiol valerate is a prodrug ester slowly hydrolyzed to estradiol, providing sustained estrogenic signalling. It activates estrogen receptors to regulate reproductive physiology, bone homeostasis and metabolic pathways.

Benefits and Advantages

Used in depot‑estrogen pharmacology, ER‑signalling research, hormone‑replacement modelling, and controlled‑release formulation development.

Side Effects and Risks

Risks include thromboembolism, breast tenderness, nausea and hepatic stimulation. Handle with estrogen‑ester precautions.

Datasheet


Molecular Formula

C23H32O3

Molecular Weight

356.5 g/mol

CAS Number

979-32-8

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

estradiol valerate; 979-32-8; Estradiol 17-valerate; Delestrogen; Climaval

IUPAC/Chemical Name

[(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] pentanoate

InChl Key

RSEPBGGWRJCQGY-RBRWEJTLSA-N

InChl Code

InChI=1S/C23H32O3/c1-3-4-5-22(25)26-21-11-10-20-19-8-6-15-14-16(24)7-9-17(15)18(19)12-13-23(20,21)2/h7,9,14,18-21,24H,3-6,8,10-13H2,1-2H3/t18-,19-,20+,21+,23+/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/13791;

3D Conformer.

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