About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Estriol (E3) is a weaker estrogen produced mainly during pregnancy. It binds ER/ER with lower affinity than estradiol but still regulates reproductive and urogenital tissues through transcriptional modulation and membraneinitiated signalling.
Benefits and Advantages
Used in lowpotency estrogen research, mucosaltissue modelling, ERligand affinity studies, and selectiveestrogen pharmacology.
Side Effects and Risks
Risks include mild nausea, breast tenderness and low but present thrombotic risk. Handle with lowpotency estrogen precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C18H24O3 |
|---|---|
| Molecular Weight | 288.4 g/mol |
| CAS Number | 50-27-1 |
| Storage Condition | Do not store above 25 °C. |
| Solubility | Slightly soluble in ethyl ether, benzene, trifluoroacetic acid; very soluble in pyridine |
| Purity | Purity information is available upon request (COA). |
| Synonym | estriol; 50-27-1; Oestriol; Trihydroxyestrin; Aacifemine |
| IUPAC/Chemical Name | (8R,9S,13S,14S,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol |
| InChl Key | PROQIPRRNZUXQM-ZXXIGWHRSA-N |
| InChl Code | InChI=1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1 |
| References |
3D Conformer.
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