About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Estradiol (E2) is the primary endogenous estrogen, binding ERα and ERβ to regulate transcription across reproductive, skeletal, cardiovascular and neural tissues. It modulates gene expression through nuclear receptor signalling and membrane‑initiated steroid signalling.
Benefits and Advantages
Used in estrogen‑receptor biology, endocrine‑signalling research, bone‑metabolism modelling, and reproductive‑physiology assays.
Side Effects and Risks
Risks include thromboembolic events, breast tenderness, nausea, endometrial stimulation and fluid retention. Handle with hormone‑modulator precautions.
Datasheet
| Molecular Formula | C18H24O2 |
|---|---|
| Molecular Weight | 272.4 g/mol |
| CAS Number | 50-28-2 |
| Storage Condition | Do not store unpouched. Apply immediately upon removal from the protective pouch. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | estradiol; beta-Estradiol; 50-28-2; 17beta-Estradiol; Oestradiol |
| IUPAC/Chemical Name | (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol |
| InChl Key | VOXZDWNPVJITMN-ZBRFXRBCSA-N |
| InChl Code | InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1 |
| References |
3D Conformer.
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