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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Product Description
Mechanism of Action
Dexamethasone sodium phosphate is a water‑soluble glucocorticoid ester enabling rapid systemic absorption. It suppresses NF‑κB signalling, reduces inflammatory mediator release, stabilizes cell membranes and alters leukocyte dynamics. Its rapid onset makes it valuable in acute inflammation research.
Benefits and Advantages
Used in acute‑inflammation modelling, rapid‑delivery steroid research, GR‑phosphorylation pathway studies, and endocrine‑suppression assays.
Side Effects and Risks
Risks include metabolic disturbances, immunosuppression, mood changes, hypertension, fluid retention and adrenal suppression. Handle with systemic‑steroid precautions.
Datasheet
| Molecular Formula | C22H28FNa2O8P |
|---|---|
| Molecular Weight | 516.4 g/mol |
| CAS Number | 2392-39-4 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | DEXAMETHASONE SODIUM PHOSPHATE; 2392-39-4; Dexamethasone 21-phosphate disodium salt; Dalalone; Dexadreson |
| IUPAC/Chemical Name | disodium;[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate |
| InChl Key | PLCQGRYPOISRTQ-FCJDYXGNSA-L |
| InChl Code | InChI=1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15+,16+,17+,19+,20+,21+,22+;;/m1../s1 |
| References |
3D Conformer.
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