DEXAMETHASON MICRONIZED
Dexamethasone is a strong glucocorticoid that suppresses inflammation and immune activity by modulating gene transcription. Used in allergies, autoimmune disease, and oncology. Side effects include hyperglycemia, mood changes, and adrenal suppression. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Micronized dexamethasone provides enhanced dissolution and bioavailability of the classic highpotency glucocorticoid. It exerts strong GRmediated antiinflammatory, immunosuppressive and antiproliferative effects by suppressing cytokines, prostaglandins and immunecell trafficking.
Benefits and Advantages
Used in inflammationpathway studies, GRactivation assays, immunosuppression modelling, and steroidbioavailability research.
Side Effects and Risks
Risks include adrenal suppression, hyperglycemia, osteoporosis, infection risk, mood disturbances and muscle wasting. Handle with systemicglucocorticoid precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C22H29FO5 |
|---|---|
| Molecular Weight | 392.46 g/mol |
| CAS Number | 50-02-2 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | Celestone; Hormezon; Bebate; .beta.-Methasone; 9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one |
| IUPAC/Chemical Name | (11β,16α)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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