DEHYDROCORTISONE ACETATE
Delamanid is a nitroimidazole derivative that inhibits mycolic acid synthesis in Mycobacterium tuberculosis. It is used in multidrug‑resistant TB regimens. Benefits include improved culture conversion when combined with other agents. Side effects include QT prolongation, nausea, and headache.
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Product Description
Mechanism of Action
Dehydrocortisone acetate is a corticosteroid derivative with reduced glucocorticoid potency. It acts through classic GR‑mediated gene regulation, decreasing inflammatory cytokines, inhibiting arachidonic‑acid pathways, and modulating carbohydrate metabolism.
Benefits and Advantages
Used in steroid‑pathway modelling, GR‑activation assays, inflammation‑suppression studies, and corticosteroid SAR research.
Side Effects and Risks
Risks include mild adrenal suppression, metabolic imbalance, fluid retention and skin thinning (topical). Handle with glucocorticoid‑class precautions.
Datasheet
| Molecular Formula | C23H30O5 |
|---|---|
| Molecular Weight | 386.48 g/mol |
| CAS Number | 53-03-2 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | methanol; methyl alcohol; 67-56-1; wood alcohol; Wood naphtha |
| IUPAC/Chemical Name | [(8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-10,13-dimethyl-3,20-dioxopregna-1,4-dien-17-yl] acetate |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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