TICARCILLIN

Ticarcillin is a broad‑spectrum penicillin effective against gram‑negative bacteria. Often combined with clavulanate. Side effects include rash, diarrhea, electrolyte imbalance, and hypersensitivity.

SKU: 0417a0a6a095 Category: Tag:

Product Description


Mechanism of Action

TICARCILLIN (ID 27669) exerts multi‑axis biochemical modulation involving enzymatic‑cascade interference, receptor‑mediated signalling adjustment, oxidative‑stress balancing, mitochondrial‑respiratory modulation, ion‑channel behaviour influence, cytoskeletal‑architecture modification and transcription‑factor regulatory alignment. Its molecular topology supports potential interaction with catalytic residues, allosteric microdomains, membrane‑anchored receptor systems and intracellular signalling scaffolds. These interactions affect phosphorylation circuits, Ca²⁺ signalling, IP₃/DAG turnover, cAMP regulation, ATP flux and cellular redox‑state stability.

Benefits & Applications

  • Receptor–ligand interaction and docking studies
  • Kinase/catalytic pathway profiling
  • Mitochondrial ATP/ROS functional modelling
  • Multi‑omics integration research
  • Cytoskeletal and membrane‑dynamics analysis
  • Apoptosis, autophagy and survival‑pathway investigations
  • SAR/QSAR modelling and molecular optimisation

Risks & Side Effects

  • ROS accumulation and oxidative‑stress imbalance
  • Mitochondrial overload or ETC suppression
  • Ion‑channel destabilisation (Ca²⁺/Na⁺/K⁺)
  • Cytoskeletal disruption and membrane integrity loss
  • Dose‑dependent cytotoxicity
  • Inflammatory cascade activation

Datasheet


Molecular Formula

C15H16N2O6S

Molecular Weight

384.4 g/mol

CAS Number

34787-01-4

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

7.16e-02 g/L

Purity

Purity information is available upon request (COA).

Synonym

TICARCILLIN; 34787-01-4; Ticarcilline; Ticarcilina; Ticarcillinum

IUPAC/Chemical Name

(2S,5R,6R)-6-[[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

InChl Key

OHKOGUYZJXTSFX-KZFFXBSXSA-N

InChl Code

InChI=1S/C15H16N2O6S2/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23)/t7-,8-,9+,12-/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/36921;

3D Conformer.

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