ERYTHROMYCIN SUCCINATE

Erythromycin succinate is a more stable and betterabsorbed macrolide prodrug used for various bacterial infections. Side effects include GI upset, diarrhea, and rash. Only GMP materials will be supplied, logistics all according to GDP.

SKU: a0cabacdf01f Category: Tag:

Product Description


Mechanism of Action

Erythromycin succinate is an acidstable ester used primarily for parenteral formulations. After hydrolysis, active erythromycin inhibits bacterial protein synthesis at the 50S ribosome.

Benefits and Advantages

Used in injectableantibiotic research, macrolide PK/PD modelling, esteractivation studies, and systemicdelivery optimization.

Side Effects and Risks

Risks include injectionsite pain, reversible hepatotoxicity, arrhythmias and allergic reactions. Handle with succinateester precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C41H71NO16

Molecular Weight

834.0 g/mol

CAS Number

10605-34-2

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Erythromycin succinate; UNII-831SF5M65L; Erythromycin, succinate (1:1) (Salt); 831SF5M65L; Erythromycin, butanedioate (1:1) (Salt)

IUPAC/Chemical Name

4-[(2S,3R,4S,6R)-4-(dimethylamino)-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-oxacyclotetradec-6-yl]oxy]-6-methyloxan-3-yl]oxy-4-oxobutanoic acid

InChl Key

HUKYDKSXFKBBIW-DTOMAXNRSA-N

InChl Code

InChI=1S/C41H71NO16/c1-14-27-41(10,51)34(47)22(4)31(46)20(2)18-39(8,50)36(58-38-33(56-29(45)16-15-28(43)44)26(42(11)12)17-21(3)53-38)23(5)32(24(6)37(49)55-27)57-30-19-40(9,52-13)35(48)25(7)54-30/h20-27,30,32-36,38,47-48,50-51H,14-19H2,1-13H3,(H,43,44)/t20-,21-,22+,23+,24-,25+,26+,27-,30+,32+,33-,34-,35+,36-,38+,39-,40-,41-/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/10328144;

3D Conformer.

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