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Product Description
Mechanism of Action
Erythromycin stearate is a hydrophobic salt designed to improve oral tolerability and acid resistance. After dissolution and absorption, it releases active erythromycin which blocks 50S‑mediated protein elongation.
Benefits and Advantages
Used in macrolide‑formulation improvement research, gastric‑acid stability studies, and oral‑bioavailability model systems.
Side Effects and Risks
Risks include mild hepatotoxicity, abdominal discomfort and hypersensitivity. Handle with macrolide‑salt precautions.
Datasheet
| Molecular Formula | C55H103NO15 |
|---|---|
| Molecular Weight | 1018.4 g/mol |
| CAS Number | 643-22-1 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | less than 1 mg/mL at 72 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | ERYTHROMYCIN STEARATE; Abboticine; Bristamycin; 643-22-1; Gallimycin |
| IUPAC/Chemical Name | (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione;octadecanoic acid |
| InChl Key | YAVZHCFFUATPRK-YZPBMOCRSA-N |
| InChl Code | InChI=1S/C37H67NO13.C18H36O2/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;2-17H2,1H3,(H,19,20)/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;/m1./s1 |
| References |
3D Conformer.
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